At-home ketamine has a credibility problem. Trellis fixes it — pairing the convenience of home dosing with the clinical rigor of a supervised psychiatric program. Not an app that mails you medicine. A treatment program that happens to reach your home.
The first wave of direct-to-consumer telehealth ketamine made a powerful medicine available to people who needed it. It also stripped away most of the structure that makes psychiatric ketamine safe: the in-person evaluation, the supervised first doses, the vital sign monitoring, the doctor who actually knows you.
That gap is now the subject of national scrutiny, regulatory attention, and litigation. The medicine was never the problem. The missing structure was.
Trellis is built on a simple premise: a patient should never take their first dose of ketamine alone, and should never take a dose at home without a real clinician standing behind the treatment.
Most telehealth ketamine starts you at home on day one. Trellis earns its way to your living room — through the clinic first.
A complete psychiatric evaluation, in person, with the prescribing physician. This establishes the medical relationship the law requires for ongoing controlled-substance care — and it means your doctor has actually met you.
Your first ketamine sessions happen in the clinic, in a monitoring chair, with vital signs tracked throughout. We learn how your body responds before you ever dose at home — and calibrate your dose to you, not to an algorithm.
Only after you've been evaluated and stabilized do you transition home — and never alone. A vetted peer monitor is present for every session, your vitals are recorded, and a clinician reviews every dose.
An honest comparison between standard direct-to-consumer telehealth ketamine and a Trellis-based program.
The same physician evaluates you, treats you, and follows your progress — not a rotating panel of strangers.
Your first sessions are in the clinic. At home, a trained peer monitor is present every single time.
A clinician is on call during every dosing window. If something feels wrong, help is one tap away.
Your vitals and your response are reviewed after each session — so your treatment adjusts to how you're actually doing.
The in-person evaluation exemption — not temporary telehealth flexibilities that may not survive the next regulatory cycle.
Vitals, attestations, peer monitor records, and your sign-off — a complete, time-stamped, immutable record on every session.
Out-of-range vitals and adverse events auto-flag for your review. Nothing waits in an inbox you didn't know to check.
Run a rigorous program without drowning in it. Trellis handles the orchestration so you can handle the medicine.
Every monitor is ID-verified, interviewed by video, and signs a consent that spells out their responsibilities and the escalation criteria.
Blood pressure at baseline, peak, and recovery. Readings outside safe thresholds halt dosing or trigger immediate clinical contact.
A structured record captured live during each session — vitals, observations, patient response — locked and queued for physician review.
A clinician is reachable for the entire dosing window. A tiered escalation ladder routes concerns to the right responder, fast.
Recurring in-person review keeps the treatment relationship current and on durable legal footing — and catches drift before it becomes risk.
Every dose is tied to a specific compounded lot — so a recall, an adverse event, or an audit can be answered in minutes, not days.
Talk to us
Tell us about your practice and we'll set up a 45-minute working session — not a sales pitch. We'll walk through evaluation, supervision, peer-monitor verification, and billing against your actual workflow.
FAQ
Eligibility, supervision, peer monitors, and billing — the questions practices ask before going live on Trellis.
Important: Ketamine is not FDA-approved for the treatment of depression or other psychiatric conditions; its use in these contexts is off-label. Compounded ketamine is not FDA-evaluated for safety or efficacy. Treatment is appropriate only for select patients following a comprehensive evaluation by a licensed physician. Trellis is clinical infrastructure software for licensed practices; it does not provide medical care or prescribe medication. Comparisons describe general characteristics of direct-to-consumer telehealth ketamine programs as a category and are not directed at any specific provider.